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Levothyroxine doses are based on weight in childrenYour dose needs may change if you gain or lose weight.
Some side effects of levothyroxine may occur that usually do not need medical attentionThese side effects may go away during treatment as your body adjusts to the medicineAlsoyour health care professional may be able to tell you about ways to prevent or reduce some of these side effectsCheck with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
The patient should be monitored closely to avoid undertreatment or overtreatmentUndertreatment may have deleterious effects on intellectual development and linear growthOvertreatment has been associated with craniosynostosis in infantsand may adversely affect the tempo of brain maturation and accelerate the bone age with resultant premature closure of the epiphyses and compromised adult stature.
Rapid restoration of normal serum T 4 concentrations is essential for preventing the adverse effects of congenital hypothyroidism on intellectual development as well as on overall physical growth and maturationThereforeSYNTHROID therapy should be initiated immediately upon diagnosis and is generally continued for life.
Animal studies have not been performed to evaluate the carcinogenic potentialmutagenic potential or effects on fertility of levothyroxineThe synthetic T 4 in SYNTHROID is identical to that produced naturally by the human thyroid glandAlthough there has been a reported association between prolonged thyroid hormone therapy and breast cancerthis has not been confirmedPatients receiving SYNTHROID for appropriate clinical indications should be titrated to the lowest effective replacement dose.
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