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There have been several cases of esophageal ulcers associated with oral tetracycline therapyIn each casethe patient had taken the medication just before bedtime with only small amounts of liquid and reported severe retrosternal pain and painful swallowing shortly thereafterThe ulcers resolved spontaneously after discontinuation of tetracycline therapyTo minimize esophageal irritationpatients should be advised to avoid taking tetracycline just before retiring and to take the medication with plenty of water.
Take this medication 2-3 hours before or after taking any products containing magnesiumaluminumor calciumSome examples include antacidsquinaprilcertain forms of didanosinechewable/dispersible buffered tablets or pediatric oral solutionvitamins/mineralsand sucralfateFollow the same instructions with dairy productse.gmilkyogurtcalcium-enriched juicebismuth subsalicylateironand zincThese products bind with tetracyclinepreventing its full absorption.
Follow all directions on your prescription labelDo not take this medicine in larger or smaller amounts or for longer than recommended.
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