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Elderly patientscompared to younger patientsare at greater risk for NSAID-associated serious cardiovasculargastrointestinaland/or renal adverse reactionsIf the anticipated benefit for the elderly patient outweighs these potential risksstart dosing at the low end of the dosing rangeand monitor patients for adverse effectssee WARNINGS AND PRECAUTIONS
There is no consistent evidence that concurrent use of aspirin mitigates the increased risk of serious CV thrombotic events associated with NSAID useThe concurrent use of aspirin and an NSAIDsuch as celecoxibincreases the risk of serious gastrointestinalGIeventssee Gastrointestinal BleedingUlcerationAnd Perforation
Chest painweaknessshortness of breathslurred speechproblems with vision or balanceblackbloodyor tarry stoolscoughing up blood or vomit that looks like coffee groundsswelling or rapid weight gainurinating less than usual or not at allnauseaupper stomach pain.
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