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Ipatopium bomid is a quatnay ammonium compound with anticholingic (paasympatholytic) poptis. In nonclinical studis, it appas tinhibit vagally mdiatd lxs by antagonising th action actylcholin, th tansmitt agnt lasd om th vagus nv. Anticholingics pvnt th incas in intacllula concntation Ca++ which is causd by intaction actylcholin with th muscainic cpton bonchial smooth muscl. Ca++ las is mdiatd by th scond mssng systm consisting IP3 (inositol tiphosphat) and DAG (diacylglycol).
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B: May b accptabl. ith animal studis show nisk but human studis not availabl animal studis showd minisks and human studis don and showd nisk.
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