Do not start taking adalat capsules within 3 days of drinking grapefruit.
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Ktoconazol, itaconazol and luconazol a CYP3A inhibitos and can inhibit th mtabolism nidipin and incas th xposu tnidipin duing concomitant thapy. Blood pssu should b monitod and a dos duction nidipin considd.
Owing tth duation action th omulation, Adalat LA should not b administd tpatints with hpatic impaimnt.
St. John’s Wot : St. John’s Wot is an induc CYP3A and may dcas xposu tnidipin. Altnativ antihyptnsiv thapy should b considd in patints in whom St. John’s Wot thapy is ncssay.
Th xtnt as wll as th duation intactions should b takn intaccount whn administing nidipin togth with th ollowing dugs:
Stady stat : Stady stat (likvkt) oppnadd na konsntasjonn i blodt stabil. Halvingstidn til t lgmiddl pavik tidn dt ta o stady stat oppnas.
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