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Hypersensitivity Reactionssee CONTRAINDICATIONSAcute Interstitial Nephritissee WARNINGS AND PRECAUTIONSClostridium difficile Associated Diarrheasee WARNINGS AND PRECAUTIONSBone Fracturesee WARNINGS AND PRECAUTIONSCutaneous and Systemic Lupus Erythematosussee WARNINGS AND PRECAUTIONSCyanocobalaminVitamin B-12Deficiencysee WARNINGS AND PRECAUTIONSHypomagnesemiasee WARNINGS AND PRECAUTIONSDrug Interactions Advise patients to let you know if they are takingor begin takingother medicationsbecause NEXIUM can interfere with antiretroviral drugs and drugs that are affected by gastric pH changessee DRUG INTERACTIONS

Clostridium difficile associated diarrheaCDADhas been reported with use of nearly all antibacterial agentsFor more information specific to antibacterial agentsclarithromycin and amoxicillinindicated for use in combination with NEXIUMrefer to WARNINGS and PRECAUTIONS sections of those package inserts.

Please refer to amoxicillin and clarithromycin prescribing information for ContraindicationsWarningsand dosing in elderly and renally-impaired patients.

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