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Nauseastomach upsetdiarrheaor weight gain may occurIf any of these effects persist or worsentell your doctor or pharmacist promptlyIf stomach symptoms return laterafter you are on the same dose for several days or weekstell your doctor right awayStomach symptoms that occur after the first days of your treatment may be a sign of lactic acidosis.

Metformin can cause a rare but serious condition known as lactic acidosisa build-up of acid in the bloodLactic acidosis can cause death and requires immediate treatmentSymptoms of lactic acidosis include:

You should not use Glucovance if you have severe kidney diseaseif you also take bosentanTracleeror if you have metabolic acidosis or diabetic ketoacidosiscall your doctor for treatment

John PCunhaDOis a U.Sboard-certified Emergency Medicine PhysicianDrCunha’s educational background includes a BS in Biology from Rutgersthe State University of New Jerseyand a DO from the Kansas City University of Medicine and Biosciences in Kansas CityMOHe completed residency training in Emergency Medicine at Newark Beth Israel Medical Center in NewarkNew Jersey.

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