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Moreoverwith Lasix treatmentthere is increased bodily excretion of calciummagnesiumand potassiumThese two mechanisms determine the diuretic and hypotensive effects of LasixAccording to the official instructionsthe drug acts after a short period and its effects persist for 1.5 to 3 hours.

Contraindications and precautions Contraindicated in patients hypersensitive to drug and patients with anuriahepatic comaor severe electrolyte depletionContraindicated if increased azotemiaoliguriaor progressive renal disease occur during therapyUse cautiously in pregnant womenpatients with sulfa allergyand in those with hepatic cirrhosis.

There is no specific antidote to treat Lasix overdoseTherapy for correcting an overdose is symptomatic and is directed at correcting and restoring water-electrolyte balance.

*Please note that Tocris will only send literature to established scientific businessinstitute addresses.

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