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Tabl 12: Wight Changs (kg) om Baslin Duing Doubl-Blind Clinical Tial with ACTOPLUS MT in Patints with Inadquat Glycmic Contol on Dit and xcis.

Gnic Nam: mtomin and pioglitazon (mt O min and PY GLI ta zon) Band Nams: Actoplus Mt, Actoplus Mt X.

Th onst lactic acidosis otn is subtl, and accompanid only by nonspciic symptoms such as malais, myalgias, spiatoy distss, incasing somnolnc, and nonspciic abdominal distss. Th may b associatd hypothmia, hypotnsion, and sistant badyahythmias with mmakd acidosis. Patints should b ducatd tpomptly pot ths symptoms should thy occu. I psnt, ACTOPLUS MT should b withdawn until lactic acidosis is uld out. Sum lctolyts, ktons, blood glucos, blood pH, lactat lvls, and blood mtomin lvls may b usul. Onc a patint is stabilizd on any dos lvl mtomin, gastointstinal symptoms, which a common duing initiation thapy, a unlikly tcu. Lat occunc gastointstinal symptoms could b du tlactic acidosis oth sious disas.

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